.Pharmacolibrary.Drugs.R_RespiratorySystem.R02A_ThroatPreparations.R02AD05_Ambroxol.Ambroxol

Information

Ambroxol is a mucolytic agent used to facilitate the clearance of mucus from the respiratory tract. It is commonly prescribed to treat acute and chronic diseases of the respiratory tract associated with viscid or excessive mucus. Ambroxol is widely approved and used in clinical practice, especially in Europe and Asia.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after oral administration.

References

1. Ni, Y, et al., & Fan, J (2016). Bioequivalence assessment of ambroxol orally-disintegrating tablet after a single oral-dose administration to healthy volunteers. International journal of clinical pharmacology and therapeutics 54(5) 399–404. DOI:10.5414/CP202527 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27007998

2. Wang, Y, et al., & Ding, L (2018). Investigation of a potential drug-drug interaction between salbutamol and ambroxol and bioequivalence of a new fixed-dose combination containing these two drugs in healthy Chinese subjects. International journal of clinical pharmacology and therapeutics 56(5) 247–254. DOI:10.5414/CP203188 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29595123

3. Villacampa, J, et al., & Rosete, R (2003). Pharmacokinetic properties of single-dose loratadine and ambroxol alone and combined in tablet formulations in healthy men. Clinical therapeutics 25(8) 2225–2232. DOI:10.1016/s0149-2918(03)80215-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14512130

Revisions

• 06/2025 initial generated model