.Pharmacolibrary.Drugs.R_RespiratorySystem.R02A_ThroatPreparations.R02AX02_Ibuprofen.Ibuprofen

Information

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used for its analgesic, anti-inflammatory, and antipyretic properties. It is widely approved and used worldwide for managing mild to moderate pain, fever, and inflammation.

Pharmacokinetics

Pharmacokinetic parameters obtained from healthy adult volunteers after single oral administration.

References

1. Moore, RA, et al., & Straube, S (2015). Effects of food on pharmacokinetics of immediate release oral formulations of aspirin, dipyrone, paracetamol and NSAIDs - a systematic review. British journal of clinical pharmacology 80(3) 381–388. DOI:10.1111/bcp.12628 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25784216

2. Thigpen, JC, et al., & Harirforoosh, S (2019). Opioids: A Review of Pharmacokinetics and Pharmacodynamics in Neonates, Infants, and Children. European journal of drug metabolism and pharmacokinetics 44(5) 591–609. DOI:10.1007/s13318-019-00552-0 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31006834

3. Sharma, PK, et al., & Narang, A (2003). Pharmacokinetics of oral ibuprofen in premature infants. Journal of clinical pharmacology 43(9) 968–973. DOI:10.1177/0091270003254635 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12971028

Revisions

• 06/2025 initial generated model