.Pharmacolibrary.Drugs.R_RespiratorySystem.R03C_AdrenergicsForSystemicUse.R03CA02_Ephedrine.Ephedrine .Pharmacolibrary.Drugs.R_RespiratorySystem.R03C_AdrenergicsForSystemicUse.R03CA02_Ephedrine.Ephedrine| name: | Ephedrine | |
| ATC code: | R03CA02 | route: | oral |
| compartments: | 1 | |
| dosage: | 50 | mg |
| volume of distribution: | 2.7 | L |
| clearance: | 23.3 | L/h |
| other parameters in model implementation | ||
Ephedrine is a sympathomimetic amine used as a medication and stimulant. It is primarily employed to prevent low blood pressure during anesthesia, for the treatment of nasal congestion, and historically as a bronchodilator for asthma. Due to potential side effects and abuse, its use for asthma and as an over-the-counter stimulant has become less common; however, it remains approved and is still used in clinical settings worldwide for specific indications.
Pharmacokinetic parameters derived from healthy adult subjects after oral administration.
Howard, DR, et al., & Agrawala, P (2005). Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults. Current medical research and opinion 21(5) 769–776. DOI:10.1185/030079905x43703 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15969876