.Pharmacolibrary.Drugs.R_RespiratorySystem.R03C_AdrenergicsForSystemicUse.R03CA02_Ephedrine.Ephedrine_1

Information

Ephedrine is a sympathomimetic amine used as a medication and stimulant. It is primarily employed to prevent low blood pressure during anesthesia, for the treatment of nasal congestion, and historically as a bronchodilator for asthma. Due to potential side effects and abuse, its use for asthma and as an over-the-counter stimulant has become less common; however, it remains approved and is still used in clinical settings worldwide for specific indications.

Pharmacokinetics

Pharmacokinetic parameters derived from healthy adult subjects after intravenous administration.

References

1. Hahn, RG (2021). Distribution of crystalloid fluid infused during onset of anesthesia-induced hypotension: a retrospective population kinetic analysis. Perioperative medicine (London, England) 10(1) 34–None. DOI:10.1186/s13741-021-00204-5 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34629113

2. Partridge, BL, et al., & Reisner, LS (1988). Life-threatening effects of intravascular absorption of PGF2 alpha during therapeutic termination of pregnancy. Anesthesia and analgesia 67(11) 1111–1113. PUBMED:https://pubmed.ncbi.nlm.nih.gov/3189904

Revisions

• 06/2025 initial generated model