.Pharmacolibrary.Drugs.R_RespiratorySystem.R03C_AdrenergicsForSystemicUse.R03CC12_Bambuterol.Bambuterol

Information

Bambuterol is a long-acting beta2-adrenergic agonist (LABA) used as a bronchodilator for the management of asthma and chronic obstructive pulmonary disease (COPD). It is a prodrug of terbutaline. Bambuterol is administered orally and is approved and used in some countries for maintenance treatment of asthma.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers, typically after single oral administration.

References

1. Ahlström, H, et al., & Rosenborg, J (1999). Pharmacokinetics of bambuterol during oral administration to asthmatic children. British journal of clinical pharmacology 48(3) 299–308. DOI:10.1046/j.1365-2125.1999.00028.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/10510139

2. Ye, Y, et al., & Tan, W (2015). The Lipid-lowering Effects of R-bambuterol in Healthy Chinese Volunteers: A Randomized Phase I Clinical Study. EBioMedicine 2(4) 356–364. DOI:10.1016/j.ebiom.2015.02.006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26137575

Revisions

• 06/2025 initial generated model