.Pharmacolibrary.Drugs.R_RespiratorySystem.R05C_ExpectorantsExclCombinationsWithCoughSuppressant.R05CB10_OxomemazineAndGuaifenesi.OxomemazineAndGuaifenesi .Pharmacolibrary.Drugs.R_RespiratorySystem.R05C_ExpectorantsExclCombinationsWithCoughSuppressant.R05CB10_OxomemazineAndGuaifenesi.OxomemazineAndGuaifenesi| name: | OxomemazineAndGuaifenesinCombinations | |
| ATC code: | R05CB10 | route: | orally |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 2.5 | L |
| clearance: | 0.05 | L/min |
| other parameters in model implementation | ||
This is a combination drug containing oxomemazine, an antihistaminic with sedative properties, and guaifenesin, an expectorant used for symptomatic relief of cough. It is used primarily as an over-the-counter cough syrup in various countries. Oxomemazine/guaifenesin combination is not approved by the FDA in the United States but is available in France and some other countries.
No published pharmacokinetic (PK) studies specifically on the oxomemazine/guaifenesin combination. Parameters estimated based on known PK of individual drugs in healthy adults.