.Pharmacolibrary.Drugs.R_RespiratorySystem.R05D_CoughSuppressantsExclCombinationsWithExpectorant.R05DA06_Normethadone.Normethadone .Pharmacolibrary.Drugs.R_RespiratorySystem.R05D_CoughSuppressantsExclCombinationsWithExpectorant.R05DA06_Normethadone.Normethadone| name: | Normethadone | |
| ATC code: | R05DA06 | route: | oral |
| compartments: | 1 | |
| dosage: | 10 | mg |
| volume of distribution: | 4 | L |
| clearance: | 0.014 | L/min/kg |
| other parameters in model implementation | ||
Normethadone is a synthetic opioid analgesic and antitussive agent related to methadone. It was previously used for the treatment of pain and as a cough suppressant, but is not currently approved or in common use due to its high potency, risk of toxicity, and potential for abuse.
Estimated pharmacokinetic parameters as direct data from human studies are not available in published literature; estimates are based on structural similarities to methadone and reference to secondary pharmacological sources.