.Pharmacolibrary.Drugs.R_RespiratorySystem.R06A_AntihistaminesForSystemicUse.R06AA61_DimenhydrinateCombinatio.DimenhydrinateCombinatio .Pharmacolibrary.Drugs.R_RespiratorySystem.R06A_AntihistaminesForSystemicUse.R06AA61_DimenhydrinateCombinatio.DimenhydrinateCombinatio| name: | DimenhydrinateCombinations | |
| ATC code: | R06AA61 | route: | oral |
| compartments: | 1 | |
| dosage: | 50 | mg |
| volume of distribution: | 3.5 | L |
| clearance: | 600 | mL/min |
| other parameters in model implementation | ||
Dimenhydrinate is an antihistamine used primarily to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It is a combination of diphenhydramine and 8-chlorotheophylline. The drug is available over-the-counter in many countries and remains widely used for motion sickness and vertigo.
Estimated pharmacokinetic parameters for healthy adults, as published data specifically for dimenhydrinate, combinations (R06AA61) are not available; estimates are based on the main active moiety diphenhydramine.