.Pharmacolibrary.Drugs.R_RespiratorySystem.R06A_AntihistaminesForSystemicUse.R06AB54_ChlorphenamineCombinatio.ChlorphenamineCombinatio .Pharmacolibrary.Drugs.R_RespiratorySystem.R06A_AntihistaminesForSystemicUse.R06AB54_ChlorphenamineCombinatio.ChlorphenamineCombinatio| name: | ChlorphenamineCombinations | |
| ATC code: | R06AB54 | route: | oral |
| compartments: | 2 | |
| dosage: | 4 | mg |
| volume of distribution: | 150 | L |
| clearance: | 24 | L/hr |
| other parameters in model implementation | ||
Chlorphenamine, often combined with other agents in cold and allergy medicines, is a first-generation antihistamine used for symptomatic relief of allergic conditions such as rhinitis, urticaria, and hay fever. It is an older medication, still in use today as an over-the-counter remedy for allergy and cold symptoms. Combinations may include analgesics, decongestants, and sometimes antitussives.
Estimated pharmacokinetics in healthy adult subjects (mixed-sex) for oral combination formulations. No direct literature source specifically for the combination product, parameters estimated based on single-agent chlorphenamine data.