.Pharmacolibrary.Drugs.R_RespiratorySystem.R06A_AntihistaminesForSystemicUse.R06AE03_Cyclizine.Cyclizine .Pharmacolibrary.Drugs.R_RespiratorySystem.R06A_AntihistaminesForSystemicUse.R06AE03_Cyclizine.Cyclizine| name: | Cyclizine | |
| ATC code: | R06AE03 | route: | oral |
| compartments: | 1 | |
| dosage: | 50 | mg |
| volume of distribution: | 16 | L |
| clearance: | 30 | L/h |
| other parameters in model implementation | ||
Cyclizine is a first-generation antihistamine with antiemetic, anticholinergic, and mild sedative properties, commonly used for the prevention and treatment of nausea, vomiting, and vertigo associated with motion sickness, postoperative states, and certain other conditions. It remains in clinical use today, though newer antiemetics are often preferred in some settings.
Pharmacokinetic parameters estimated for healthy adult individuals after oral administration due to lack of detailed compartmental modeling in the literature.