.Pharmacolibrary.Drugs.S_SensoryOrgans.S01A_Antiinfectives.S01AD03_Aciclovir.Aciclovir

Information

Aciclovir is an antiviral medication primarily used for the treatment of herpes simplex virus and varicella-zoster virus infections, including shingles and genital herpes. It is well-established and widely approved for clinical use in many countries.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after a single oral dose of aciclovir.

References

1. O'Brien, JJ, & Campoli-Richards, DM (1989). Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy. Drugs 37(3) 233–309. DOI:10.2165/00003495-198937030-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2653790

2. Patel, R (1997). Valaciclovir: development, clinical utility and potential. Expert opinion on investigational drugs 6(2) 173–189. DOI:10.1517/13543784.6.2.173 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15989601

3. Noble, S, & Faulds, D (1998). Ganciclovir. An update of its use in the prevention of cytomegalovirus infection and disease in transplant recipients. Drugs 56(1) 115–146. DOI:10.2165/00003495-199856010-00012 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9664203

Revisions

• 06/2025 initial generated model