.Pharmacolibrary.Drugs.S_SensoryOrgans.S01A_Antiinfectives.S01AE05_Levofloxacin.Levofloxacin_1

Information

Levofloxacin is a broad-spectrum fluoroquinolone antibiotic used for the treatment of various bacterial infections, including respiratory tract infections, urinary tract infections, and skin infections. It is an approved medication and is widely used in clinical practice.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following intravenous administration.

References

1. Setiawan, E, et al., & Roberts, JA (2022). Population pharmacokinetics and dose optimization of intravenous levofloxacin in hospitalized adult patients. Scientific reports 12(1) 8930–None. DOI:10.1038/s41598-022-12627-1 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35624222

2. Zhang, Y, et al., & Sun, L (2014). Population pharmacokinetics of intravenous levofloxacin 500 mg/day dosage in infected patients. Die Pharmazie 69(7) 553–557. PUBMED:https://pubmed.ncbi.nlm.nih.gov/25073403

3. Jaruratanasirikul, S, et al., & Samaeng, M (2018). Population Pharmacokinetics and Pharmacodynamics Modeling of Oral Levofloxacin. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 99(8) 886–892. PUBMED:https://pubmed.ncbi.nlm.nih.gov/29947489

Revisions

• 06/2025 initial generated model