.Pharmacolibrary.Drugs.S_SensoryOrgans.S01B_AntiinflammatoryAgents.S01BA03_Cortisone.Cortisone .Pharmacolibrary.Drugs.S_SensoryOrgans.S01B_AntiinflammatoryAgents.S01BA03_Cortisone.Cortisone| name: | Cortisone | |
| ATC code: | S01BA03 | route: | topical |
| compartments: | 1 | |
| dosage: | 5 | mg |
| volume of distribution: | 1.5 | L |
| clearance: | 20 | L/h |
| other parameters in model implementation | ||
Cortisone is a corticosteroid hormone used for its anti-inflammatory and immunosuppressive properties. It is historically used to treat a variety of conditions such as arthritis, allergies, and skin diseases. Today, cortisone itself is less commonly used, with other corticosteroids preferred for systemic use; cortisone acetate is its active prodrug. In ophthalmology (as per ATC S01BA03), cortisone has been studied for topical use in eye disorders.
Estimated pharmacokinetic parameters for cortisone ophthalmic administration in adults. No specific clinical PK study for topical (ophthalmic) use of cortisone is available, so estimates are based on general corticosteroid properties.