.Pharmacolibrary.Drugs.S_SensoryOrgans.S01B_AntiinflammatoryAgents.S01BA04_Prednisolone.Prednisolone

Information

Prednisolone is a synthetic glucocorticoid corticosteroid drug that exhibits anti-inflammatory and immunosuppressive properties. It is primarily used for the treatment of a wide range of inflammatory and autoimmune diseases, such as asthma, rheumatoid arthritis, and allergic reactions, as well as certain eye conditions. Prednisolone is approved for use today in various formulations, including ophthalmic preparations.

Pharmacokinetics

Pharmacokinetic data reported in healthy adult subjects after a single oral administration.

References

1. de Truchis, C, et al., & Boyer, O (2023). Prednisolone pharmacokinetics after oral prednisone administration in paediatric patients with kidney transplant. British journal of clinical pharmacology 89(5) 1532–1540. DOI:10.1111/bcp.15610 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36510685

2. Petersen, KB, et al., & Schmiegelow, K (2003). Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology 51(6) 465–473. DOI:10.1007/s00280-003-0602-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12698270

3. Yoshida, K, et al., & Chanu, P (2021). Population Pharmacokinetics of Ipatasertib and Its Metabolite in Cancer Patients. Journal of clinical pharmacology 61(12) 1579–1591. DOI:10.1002/jcph.1942 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34273118

Revisions

• 06/2025 initial generated model