.Pharmacolibrary.Drugs.S_SensoryOrgans.S01E_AntiglaucomaPreparationsAndMiotics.S01EC01_Acetazolamide.Acetazolamide .Pharmacolibrary.Drugs.S_SensoryOrgans.S01E_AntiglaucomaPreparationsAndMiotics.S01EC01_Acetazolamide.Acetazolamide| name: | Acetazolamide | |
| ATC code: | S01EC01 | route: | oral |
| compartments: | 1 | |
| dosage: | 250 | mg |
| volume of distribution: | 0.2 | L |
| clearance: | 4.8 | mL/min/kg |
| other parameters in model implementation | ||
Acetazolamide is a carbonic anhydrase inhibitor used primarily to treat glaucoma, altitude sickness, epilepsy, and certain types of edema. It is also used as a diuretic. It is an approved and widely used medication in clinical practice.
Reported pharmacokinetic parameters in healthy adult volunteers after oral administration.
Downing, GJ, et al., & Alon, U (1992). Kidney function in very low birth weight infants with furosemide-related renal calcifications at ages 1 to 2 years. The Journal of pediatrics 120(4 Pt 1) 599–604. DOI:10.1016/s0022-3476(05)82490-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1552401