.Pharmacolibrary.Drugs.S_SensoryOrgans.S01E_AntiglaucomaPreparationsAndMiotics.S01EE03_Bimatoprost.Bimatoprost

Information

Bimatoprost is a synthetic prostamide analog used primarily to reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It is approved for ophthalmic use and is widely prescribed today.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following topical ocular administration.

References

1. Goldberg, I, et al., & Bejanian, M (2014). Bimatoprost 0.03%/timolol 0.5% preservative-free ophthalmic solution versus bimatoprost 0.03%/timolol 0.5% ophthalmic solution (Ganfort) for glaucoma or ocular hypertension: a 12-week randomised controlled trial. The British journal of ophthalmology 98(7) 926–931. DOI:10.1136/bjophthalmol-2013-304064 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24667994

2. Day, DG, et al., & Bejanian, M (2013). Bimatoprost 0.03% preservative-free ophthalmic solution versus bimatoprost 0.03% ophthalmic solution (Lumigan) for glaucoma or ocular hypertension: a 12-week, randomised, double-masked trial. The British journal of ophthalmology 97(8) 989–993. DOI:10.1136/bjophthalmol-2012-303040 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23743437

3. DuBiner, HB, & Hubatsch, DA (2014). Late-day intraocular pressure-lowering efficacy and tolerability of travoprost 0.004% versus bimatoprost 0.01% in patients with open-angle glaucoma or ocular hypertension: a randomized trial. BMC ophthalmology 14 151–None. DOI:10.1186/1471-2415-14-151 PUBMED:https://pubmed.ncbi.nlm.nih.gov/25432143

Revisions

• 06/2025 initial generated model