.Pharmacolibrary.Drugs.S_SensoryOrgans.S01E_AntiglaucomaPreparationsAndMiotics.S01EE06_LatanoprosteneBunod.LatanoprosteneBunod .Pharmacolibrary.Drugs.S_SensoryOrgans.S01E_AntiglaucomaPreparationsAndMiotics.S01EE06_LatanoprosteneBunod.LatanoprosteneBunod| name: | LatanoprosteneBunod | |
| ATC code: | S01EE06 | route: | ocular |
| compartments: | 1 | |
| dosage: | 0.001 | mg |
| volume of distribution: | 0.1 | L |
| clearance: | 0.01 | L/h/kg |
| other parameters in model implementation | ||
Latanoprostene bunod is a prostaglandin F2α analog indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It is an ophthalmic solution approved for use in adults. The drug is hydrolyzed in the eye to produce two active moieties: latanoprost acid and nitric oxide, both contributing to IOP reduction.
Pharmacokinetic parameters are not reported in peer-reviewed publications for latanoprostene bunod in humans. Based on estimated model for topically administered ophthalmic prostaglandin analogs.