.Pharmacolibrary.Drugs.S_SensoryOrgans.S01G_DecongestantsAndAntiallergics.S01GA02_Tetryzoline.Tetryzoline .Pharmacolibrary.Drugs.S_SensoryOrgans.S01G_DecongestantsAndAntiallergics.S01GA02_Tetryzoline.Tetryzoline| name: | Tetryzoline |
| ATC code: | S01GA02 | route: | ocular |
| n-compartments | 1 |
Tetryzoline (also known as tetrahydrozoline) is an imidazoline derivative used as a topical decongestant for the relief of eye redness and minor irritation, typically available in over-the-counter ophthalmic solutions. It acts as an alpha-adrenergic receptor agonist, leading to vasoconstriction of conjunctival blood vessels. It is approved and widely available as an ingredient in eye drops for temporary relief of redness.
No human pharmacokinetic parameters have been reported for tetryzoline in peer-reviewed literature for ocular or oral exposure. Pharmacokinetic parameters below are estimated based on limited data from animal studies and typical topical ophthalmic formulation usage.