.Pharmacolibrary.Drugs.S_SensoryOrgans.S01G_DecongestantsAndAntiallergics.S01GA06_Oxedrine.Oxedrine .Pharmacolibrary.Drugs.S_SensoryOrgans.S01G_DecongestantsAndAntiallergics.S01GA06_Oxedrine.Oxedrine| name: | Oxedrine | |
| ATC code: | S01GA06 | route: | ophthalmic |
| compartments: | 1 | |
| dosage: | 2.5 | mg |
| volume of distribution: | 50 | L |
| clearance: | 60 | L/h |
| other parameters in model implementation | ||
Oxedrine (also known as synephrine) is a sympathomimetic agent that acts as an adrenergic agonist, primarily at alpha-adrenergic receptors. It has been used in the past for its vasoconstrictive and pressor effects, especially as a mydriatic or vasoconstrictor in ophthalmic preparations. Currently, its use in mainstream medicine has diminished and it is not widely approved or used today as a first-line therapy.
No pharmacokinetic studies of oxedrine for ophthalmologic or systemic use with reported parameters found in peer-reviewed literature. The following parameters are estimated based on general knowledge of adrenergic agonist pharmacokinetics of similar drugs.