.Pharmacolibrary.Drugs.S_SensoryOrgans.S01G_DecongestantsAndAntiallergics.S01GX08_Ketotifen.Ketotifen

Information

Ketotifen is a second-generation non-competitive H1-antihistamine and mast cell stabilizer mainly used in the management of allergic conjunctivitis (as ophthalmic solution) and formerly for asthma prophylaxis and allergic conditions. Its oral use for asthma is largely discontinued today due to modest efficacy, but ophthalmic formulations remain approved and widely used.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after oral administration.

References

1. McFadyen, ML, et al., & Ludden, TM (1997). Ketotifen pharmacokinetics in children with atopic perennial asthma. European journal of clinical pharmacology 52(5) 383–386. DOI:10.1007/s002280050305 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9272408

Revisions

• 06/2025 initial generated model