.Pharmacolibrary.Drugs.S_SensoryOrgans.S01G_DecongestantsAndAntiallergics.S01GX12_Cetirizine.Cetirizine

Information

name:Cetirizine
ATC code:S01GX12
route:oral
n-compartments1

Cetirizine is a second-generation antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It is commonly used for the treatment of allergic rhinitis and chronic urticaria. Cetirizine is approved and widely used today.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after a single oral dose.

References

  1. Paine, SW, et al., & Hincks, PR (2022). Plasma and urine pharmacokinetics of hydroxyzine and cetirizine following repeated oral administrations to exercised horses. Journal of veterinary pharmacology and therapeutics 45(1) 46–53. DOI:10.1111/jvp.13010 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34469007

  2. Knych, HK, et al., & McKemie, DS (2019). Pharmacokinetics of hydroxyzine and cetirizine following oral administration of hydroxyzine to exercised Thoroughbred horses. Journal of veterinary pharmacology and therapeutics 42(6) 617–623. DOI:10.1111/jvp.12808 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31490561

  3. Hussein, Z, et al., & Stockis, A (2005). Retrospective population pharmacokinetics of levocetirizine in atopic children receiving cetirizine: the ETAC study. British journal of clinical pharmacology 59(1) 28–37. DOI:10.1111/j.1365-2125.2005.02242.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/15606437

Revisions


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