.Pharmacolibrary.Drugs.S_SensoryOrgans.S01X_OtherOphthalmologicals.S01XA15_AscorbicAcid.AscorbicAcid

Information

Ascorbic acid, also known as vitamin C, is an essential nutrient involved in tissue repair, enzymatic production of certain neurotransmitters, and immune function. It acts as an antioxidant and is used to prevent and treat vitamin C deficiency, including scurvy. Ascorbic acid ophthalmic, corresponding to ATC code S01XA15, is used topically in the eye for aiding corneal healing and reducing oxidative stress. It is approved for clinical use in many regions.

Pharmacokinetics

Pharmacokinetic parameters estimated for topical ophthalmic administration in adults; limited published PK data specific to ophthalmic use.

References

1. Kim, M, et al., & Jung, H (2014). Novel cosmetic patches for wrinkle improvement: retinyl retinoate- and ascorbic acid-loaded dissolving microneedles. International journal of cosmetic science 36(3) 207–212. DOI:10.1111/ics.12115 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24910870

2. Johnson, EJ, et al., & Lang, JC (2014). Bioavailability of AREDS1 micronutrients from softgel capsules and tablets: a pilot study. Molecular vision 20 1228–1242. PUBMED:https://pubmed.ncbi.nlm.nih.gov/25352732

Revisions

• 06/2025 initial generated model