.Pharmacolibrary.Drugs.S_SensoryOrgans.S01X_OtherOphthalmologicals.S01XA28_Varenicline.Varenicline .Pharmacolibrary.Drugs.S_SensoryOrgans.S01X_OtherOphthalmologicals.S01XA28_Varenicline.Varenicline| name: | Varenicline | |
| ATC code: | S01XA28 | route: | ophthalmic |
| compartments: | 1 | |
| dosage: | 1 | mg |
| volume of distribution: | 210 | L |
| clearance: | 10.5 | L/h |
| other parameters in model implementation | ||
Varenicline is a partial agonist at the α4β2 nicotinic acetylcholine receptor, used as a smoking cessation aid to reduce nicotine craving and withdrawal symptoms. It is approved for use in many countries and is generally administered orally.
Pharmacokinetic data for varenicline ophthalmic solution (S01XA28) is not available in published sources. Estimated parameters are derived based on extrapolation from oral varenicline, as there are currently no peer-reviewed studies reporting PK for the ocular route.