.Pharmacolibrary.Drugs.S_SensoryOrgans.S02A_Antiinfectives.S02AA08_Tetracycline.Tetracycline

Information

name:Tetracycline
ATC code:S02AA08
route:oral
n-compartments1

Tetracycline is a broad-spectrum antibiotic belonging to the tetracycline class, used primarily to treat a variety of bacterial infections including respiratory tract infections, urinary tract infections, skin infections such as acne, and certain sexually transmitted infections. It is generally approved for use but its clinical application has diminished in some regions due to the emergence of resistance and the availability of newer, more effective antibiotics.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers after single oral dose.

References

  1. Tao, RE, et al., & Feldman, SR (2023). Oral Tetracycline-Class Drugs in Dermatology: Impact of Food Intake on Absorption and Efficacy. Antibiotics (Basel, Switzerland) 12(7) –. DOI:10.3390/antibiotics12071152 PUBMED:https://pubmed.ncbi.nlm.nih.gov/37508248

  2. Thompson, EJ, et al., & Hornik, CP (2019). Population Pharmacokinetics of Doxycycline in Children. Antimicrobial agents and chemotherapy 63(12) –. DOI:10.1128/AAC.01508-19 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31548185

  3. Rodvold, KA, et al., & Pai, MP (2020). Omadacycline: A Review of the Clinical Pharmacokinetics and Pharmacodynamics. Clinical pharmacokinetics 59(4) 409–425. DOI:10.1007/s40262-019-00843-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31773505

Revisions


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