.Pharmacolibrary.Drugs.S_SensoryOrgans.S02D_OtherOtologicals.S02DA30_PolymyxinBAndNeomycinCom.PolymyxinBAndNeomycinCom .Pharmacolibrary.Drugs.S_SensoryOrgans.S02D_OtherOtologicals.S02DA30_PolymyxinBAndNeomycinCom.PolymyxinBAndNeomycinCom| name: | PolymyxinBAndNeomycinCombination |
| ATC code: | S02DA30 | route: | otic |
| n-compartments | 1 |
A combination of polymyxin B and neomycin (ATC code S02DA30), used as an otic (ear) solution for the treatment of bacterial infections of the external ear. Such combinations typically include hydrocortisone or other anti-inflammatory agents. While once widely used, some of these combinations have become less common in modern therapy, but are still available in some regions and formulations.
No published pharmacokinetic data found specifically for the combination product polymyxin B and neomycin administered otically in healthy adults or children. Pharmacokinetic parameters estimated based on data available for individual drugs administered via systemic or topical routes; minimal systemic absorption expected with otic administration unless tympanic membrane is perforated.