.Pharmacolibrary.Drugs.S_SensoryOrgans.S03B_Corticosteroids.S03BA01_Dexamethasone.Dexamethasone_1 .Pharmacolibrary.Drugs.S_SensoryOrgans.S03B_Corticosteroids.S03BA01_Dexamethasone.Dexamethasone_1| name: | Dexamethasone_1 |
| ATC code: | S03BA01_1 | route: | oral |
| n-compartments | 2 |
Dexamethasone is a potent synthetic corticosteroid used for its anti-inflammatory and immunosuppressant effects. It is used to treat a variety of conditions including allergic reactions, asthma, rheumatic problems, certain cancers, and for the management of cerebral edema. It remains widely approved and used in clinical practice.
Pharmacokinetic parameters reported for healthy subjects following single oral administration.
Wen, J, et al., & Gonzalez, D (2024). Pharmacokinetics of Dexamethasone in Children and Adolescents with Obesity. Journal of clinical pharmacology 64(12) 1491–1504. DOI:10.1002/jcph.6108 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39120865
Wang, X, et al., & Kansra, V (2019). Population Pharmacokinetics of Rolapitant in Patients With Chemotherapy-Induced Nausea and Vomiting. Clinical pharmacology in drug development 8(7) 850–860. DOI:10.1002/cpdd.733 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31418538
Nakade, S, et al., & Miyata, Y (2008). Population pharmacokinetics of aprepitant and dexamethasone in the prevention of chemotherapy-induced nausea and vomiting. Cancer chemotherapy and pharmacology 63(1) 75–83. DOI:10.1007/s00280-008-0713-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/18317761