.Pharmacolibrary.Drugs.S_SensoryOrgans.S03B_Corticosteroids.S03BA02_Prednisolone.Prednisolone

Information

Prednisolone is a synthetic glucocorticoid drug with anti-inflammatory and immunosuppressive properties. It is widely used for the treatment of various inflammatory and autoimmune conditions, such as allergies, asthma, rheumatoid arthritis, and certain eye disorders. It is an approved medication and is still used clinically today.

Pharmacokinetics

Pharmacokinetic parameters observed in healthy adult subjects after oral administration of prednisolone.

References

1. de Truchis, C, et al., & Boyer, O (2023). Prednisolone pharmacokinetics after oral prednisone administration in paediatric patients with kidney transplant. British journal of clinical pharmacology 89(5) 1532–1540. DOI:10.1111/bcp.15610 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36510685

2. Petersen, KB, et al., & Schmiegelow, K (2003). Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology 51(6) 465–473. DOI:10.1007/s00280-003-0602-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12698270

3. Yoshida, K, et al., & Chanu, P (2021). Population Pharmacokinetics of Ipatasertib and Its Metabolite in Cancer Patients. Journal of clinical pharmacology 61(12) 1579–1591. DOI:10.1002/jcph.1942 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34273118

Revisions

• 06/2025 initial generated model