.Pharmacolibrary.Drugs.S_SensoryOrgans.S03B_Corticosteroids.S03BA03_Betamethasone.Betamethasone_1

Information

name:Betamethasone_1
ATC code:S03BA03_1
route:oral
n-compartments1

Betamethasone is a potent synthetic glucocorticoid corticosteroid with anti-inflammatory and immunosuppressive properties. It is used in the treatment of various inflammatory, allergic, and autoimmune disorders. It is approved and widely used in contemporary medicine, including formulations for ophthalmic, topical, and systemic use.

Pharmacokinetics

Estimated typical parameters for oral administration in adults (when used off-label), as no specific PK publication exists for oral betamethasone.

References

  1. Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(2) 261–272. DOI:10.1007/s10928-020-09730-z PUBMED:https://pubmed.ncbi.nlm.nih.gov/33389521

  2. Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(3) 411–438. DOI:10.1007/s10928-021-09755-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/33954911

  3. Lim, SY, et al., & Heard, CM (2020). Mucoadhesive thin films for the simultaneous delivery of microbicide and anti-inflammatory drugs in the treatment of periodontal diseases. International journal of pharmaceutics 573 118860–None. DOI:10.1016/j.ijpharm.2019.118860 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31759104

Revisions


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