name: | Betamethasone_1 |
ATC code: | S03BA03_1 | route: | oral |
n-compartments | 1 |
Betamethasone is a potent synthetic glucocorticoid corticosteroid with anti-inflammatory and immunosuppressive properties. It is used in the treatment of various inflammatory, allergic, and autoimmune disorders. It is approved and widely used in contemporary medicine, including formulations for ophthalmic, topical, and systemic use.
Estimated typical parameters for oral administration in adults (when used off-label), as no specific PK publication exists for oral betamethasone.
Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacokinetic modeling of intramuscular and oral dexamethasone and betamethasone in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(2) 261–272. DOI:10.1007/s10928-020-09730-z PUBMED:https://pubmed.ncbi.nlm.nih.gov/33389521
Krzyzanski, W, et al., & Jusko, WJ (2021). Population pharmacodynamic modeling of intramuscular and oral dexamethasone and betamethasone effects on six biomarkers with circadian complexities in Indian women. Journal of pharmacokinetics and pharmacodynamics 48(3) 411–438. DOI:10.1007/s10928-021-09755-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/33954911
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