.Pharmacolibrary.Drugs.V_Various.V03A_AllOtherTherapeuticProducts.V03AB27_D_4Dimethylaminophenol.D_4Dimethylaminophenol

Information

name: D_4Dimethylaminophenol
ATC code: V03AB27
route: intramuscular
compartments: 1
dosage: 250 mg
volume of distribution: 2.0 L
clearance: 10 L/h
other parameters in model implementation

4-dimethylaminophenol (DMAP) is an aromatic amine used as an antidote to cyanide poisoning, primarily by inducing methemoglobinemia, which binds cyanide ions to form the non-toxic cyanomethemoglobin. It is not generally approved for clinical use in most countries today and is mainly used in emergency or experimental settings, particularly in some European countries.

Pharmacokinetics

Pharmacokinetic parameters have not been reported in peer-reviewed clinical or preclinical studies in humans. All values below are estimates based on related properties of aromatic amines and known clinical usage.

References

Revisions


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