.Pharmacolibrary.Drugs.V_Various.V03A_AllOtherTherapeuticProducts.V03AB36_Phentolamine.Phentolamine .Pharmacolibrary.Drugs.V_Various.V03A_AllOtherTherapeuticProducts.V03AB36_Phentolamine.Phentolamine| name: | Phentolamine | |
| ATC code: | V03AB36 | |
| route: | intravenous | |
| compartments: | 2 | |
| dosage: | 5 | mg |
| volume of distribution: | 1.9 | L |
| clearance: | 110 | mL/min |
| other parameters in model implementation | ||
Phentolamine is a non-selective alpha-adrenergic antagonist used historically for the management of hypertensive emergencies, especially associated with pheochromocytoma and extravasation of vasoconstrictors. It is also used diagnostically in the pheochromocytoma challenge test. As of today, it is approved and available in some countries but is not widely used in general clinical practice.
Pharmacokinetic data primarily based on healthy adult subjects, intravenous administration.