.Pharmacolibrary.Drugs.V_Various.V03A_AllOtherTherapeuticProducts.V03AF01_Mesna.Mesna .Pharmacolibrary.Drugs.V_Various.V03A_AllOtherTherapeuticProducts.V03AF01_Mesna.Mesna| name: | Mesna |
| ATC code: | V03AF01 | route: | intravenous |
| n-compartments | 2 |
Mesna (sodium 2-mercaptoethane sulfonate) is a uroprotective agent used to reduce the incidence of hemorrhagic cystitis caused by oxazaphosphorine chemotherapy agents such as ifosfamide and cyclophosphamide. It acts by binding toxic urotoxic metabolites in urine, and it is approved and widely used as a supportive care medication during chemotherapy.
Pharmacokinetic parameters of mesna after intravenous administration in adult cancer patients undergoing chemotherapy. Parameters are based on studies of typical dosing in adults.
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