.Pharmacolibrary.Drugs.V_Various.V04C_OtherDiagnosticAgents.V04CD04_Corticorelin.Corticorelin .Pharmacolibrary.Drugs.V_Various.V04C_OtherDiagnosticAgents.V04CD04_Corticorelin.Corticorelin| name: | Corticorelin | |
| ATC code: | V04CD04 | route: | intravenous |
| compartments: | 1 | |
| dosage: | 1 | mg |
| volume of distribution: | 0.2 | L |
| clearance: | 1.2 | L/h/kg |
| other parameters in model implementation | ||
Corticorelin, also known as ovine corticotropin-releasing hormone (oCRH), is a synthetic peptide analog of the naturally occurring hypothalamic peptide corticotropin-releasing hormone. It is mainly used as a diagnostic agent to differentiate between pituitary (Cushing's disease) and ectopic sources of adrenocorticotropic hormone (ACTH) in the evaluation of Cushing's syndrome. Corticorelin is approved for human use as a diagnostic aid, not for therapeutic purposes.
Estimated pharmacokinetics in healthy adults, as no published population PK study is available. Most dosing is by single intravenous administration for diagnostic purposes.