.Pharmacolibrary.Drugs.V_Various.V04C_OtherDiagnosticAgents.V04CX02_FolicAcid.FolicAcid

Information

Folic acid is a water-soluble B-vitamin (vitamin B9) essential for DNA synthesis, repair, and methylation as well as amino acid metabolism. It is commonly used to prevent and treat folate deficiency, including megaloblastic anemia, and is recommended for women planning pregnancy to prevent neural tube defects. Folic acid is an approved and widely used drug.

Pharmacokinetics

Healthy adult volunteers, oral administration, fasting state.

References

1. Lee, SK (2023). Issues of Women with Epilepsy and Suitable Antiseizure Drugs. Journal of epilepsy research 13(2) 23–35. DOI:10.14581/jer.23005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38223363

2. Genton, P, et al., & Trinka, E (2006). Valproic acid in epilepsy : pregnancy-related issues. Drug safety 29(1) 1–21. DOI:10.2165/00002018-200629010-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16454531

3. Bayes, J, et al., & Schloss, J (2019). The Bioavailability of Various Oral Forms of Folate Supplementation in Healthy Populations and Animal Models: A Systematic Review. Journal of alternative and complementary medicine (New York, N.Y.) 25(2) 169–180. DOI:10.1089/acm.2018.0086 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30010385

Revisions

• 06/2025 initial generated model