.Pharmacolibrary.Drugs.V_Various.V04C_OtherDiagnosticAgents.V04CX05_D_13cUrea.D_13cUrea

Information

name:D_13cUrea
ATC code:V04CX05
route:orally
n-compartments1

13C-urea is a stable isotope-labeled form of urea used primarily as a diagnostic agent in the 13C-urea breath test for the detection of Helicobacter pylori infection. It is not used as a therapeutic agent and is approved for diagnostic use in many countries.

Pharmacokinetics

Pharmacokinetics estimated for healthy adults undergoing the 13C-urea breath test. No specific PK publication found; the parameters are based on general urea kinetics and clinical use of the test.

References

  1. Hu, YM, et al., & Xu, SY (2005). Pharmacodynamic effects and kinetic disposition of rabeprazole in relation to CYP2C19 genotype in healthy Chinese subjects. Acta pharmacologica Sinica 26(3) 384–388. DOI:10.1111/j.1745-7254.2005.00047.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/15715938

Revisions


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