.Pharmacolibrary.Drugs.V_Various.V08C_MagneticResonanceImagingContrastMedia.V08CA09_Gadobutrol.Gadobutrol .Pharmacolibrary.Drugs.V_Various.V08C_MagneticResonanceImagingContrastMedia.V08CA09_Gadobutrol.Gadobutrol| name: | Gadobutrol | |
| ATC code: | V08CA09 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 0.1 | mg |
| volume of distribution: | 0.16 | L |
| clearance: | 1.1 | mL/min/kg |
| other parameters in model implementation | ||
Gadobutrol is a nonionic, macrocyclic gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to enhance the visualization of blood vessels and detect abnormalities in the brain, spine, and other tissues. It is widely approved and used in clinical practice for diagnostic imaging.
Pharmacokinetic parameters reported in healthy adult volunteers after single intravenous administration.
Hahn, G, et al., & Mentzel, HJ (2009). Pharmacokinetics and safety of gadobutrol-enhanced magnetic resonance imaging in pediatric patients. Investigative radiology 44(12) 776–783. DOI:10.1097/RLI.0b013e3181bfe2d2 PUBMED:https://pubmed.ncbi.nlm.nih.gov/19858730