.Pharmacolibrary.Drugs.V_Various.V09I_TumourDetection.V09IX10_FluoroethylLTyrosine18f.FluoroethylLTyrosine18f .Pharmacolibrary.Drugs.V_Various.V09I_TumourDetection.V09IX10_FluoroethylLTyrosine18f.FluoroethylLTyrosine18f| name: | FluoroethylLTyrosine18f |
| ATC code: | V09IX10 | route: | intravenous |
| n-compartments | 2 |
Fluoroethyl-L-tyrosine (18F), commonly referred to as [18F]FET, is a radiolabeled amino acid analog used primarily as a positron emission tomography (PET) tracer for oncological imaging, particularly for the detection and delineation of brain tumors such as gliomas. It is not a therapeutic drug but a diagnostic radiopharmaceutical. [18F]FET is not used as a treatment and does not have traditional pharmacodynamics; its utility is in differentiating tumor tissue from healthy or necrotic tissue by exploiting increased amino acid transport in neoplastic cells.
Pharmacokinetic data refers to healthy volunteers and glioma patients undergoing [18F]FET PET imaging; typical PK values are drawn from kinetic modeling studies of brain and plasma distribution.