.Pharmacolibrary.Drugs.V_Various.V09X_OtherDiagnosticRadiopharmaceuticals.V09XA01_Iodine131iNorcholesterol.Iodine131iNorcholesterol .Pharmacolibrary.Drugs.V_Various.V09X_OtherDiagnosticRadiopharmaceuticals.V09XA01_Iodine131iNorcholesterol.Iodine131iNorcholesterol| name: | Iodine131iNorcholesterol |
| ATC code: | V09XA01 | route: | intravenous |
| n-compartments | 1 |
Iodine (131I) norcholesterol, also known as 131I-6-β-iodomethyl-norcholesterol or NP-59, is a radiolabeled cholesterol analog used primarily as a diagnostic agent in nuclear medicine for adrenal imaging and assessment of adrenal cortical function. It is not used as a therapeutic drug, and its clinical use is rare today, generally reserved for specialized diagnostic evaluation.
No comprehensive population pharmacokinetic studies providing explicit parameter values for 131I norcholesterol in humans were identified. Available information is limited to clinical imaging reports and radiotracer kinetics in small-scale studies. The following parameters are estimated based on general radioactive cholesterol analog behavior and clinical nuclear medicine use.