name: | Lutetium177luOxodotreotide |
ATC code: | V10XX04 | route: | intravenous |
n-compartments | 2 |
Lutetium (177Lu) oxodotreotide is a radiolabeled somatostatin analog used in peptide receptor radionuclide therapy (PRRT) for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). It binds to somatostatin receptors overexpressed on tumor cells, allowing targeted delivery of beta-radiation. Approved for clinical use, notably as Lutathera.
Population pharmacokinetics in adult patients with advanced, progressive, somatostatin receptor-positive GEP-NETs after intravenous administration.