.Pharmacolibrary.Examples.PKPG_1C_GentamicineEquation

Information

Pharmacogenomic (PGx) models seeks to quantify how inherited genetic variation modulates both drug pharmacokinetics and pharmacodynamics.

Example equation mode of 1-compartment PK model of gentamicine modified by PGx influence on clearance rate. Clearance rate can be influenced by  SLC22A2 genotype. Clearance is changed by PGx using ClearanceModifier instance.


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