modelDirectAbsorption

parenteral route (IV/IA): administered mass-flow reaches the port immediately

Extends from Pharmacolibrary.Sources.Absorption.PartialAbsorption (route interface: administered mass-flow in -> drug delivered at cport).

Information

DirectAbsorption

Parenteral route (intravenous, intra-arterial): the administered mass-flow is delivered to the central compartment with no depot dynamics, scaled by bioavailability:

  cport.qm = -F * mdot

Parameters

TypeNameDefaultDescription
RealF (from PartialAbsorption)1bioavailability [0-1]
Modelica.Units.SI.TimeTlag (from PartialAbsorption)0lag between administration and delivery; applied by the dose schedule (PeriodicDose starts its pulses Tlag later)

Connectors

TypeNameDefaultDescription
Modelica.Blocks.Interfaces.RealInputmdot (from PartialAbsorption)administered drug mass flow [kg/s]
Pharmacolibrary.Interfaces.ConcentrationPort_bcport (from PartialAbsorption)drug delivery to the central compartment