modelAllosteric_Hemoglobin2_MWC
Allosteric hemoglobin model implemented by Speciation blocks
Extends from Chemical.Examples.Hemoglobin.Allosteric_Hemoglobin2_MWC (Monod,Wyman,Changeux (1965) - The same allosteric hemoglobin model as Allosteric_Hemoglobin_MWC implemented by Speciation blocks).
Parameters
| Type | Name | Default | Description |
|---|---|---|---|
| Types.MolarEnergy | dHT (from Allosteric_Hemoglobin2_MWC) | 10000 | Enthalpy of heme oxygenation in T hemoglobin form |
| Types.MolarEnergy | dHR (from Allosteric_Hemoglobin2_MWC) | 20000 | Enthalpy of heme oxygenation in R hemoglobin form |
| Types.MolarEnergy | dHL (from Allosteric_Hemoglobin2_MWC) | -1000 | Enthalpy of reaction T->R as hemoglobin tetramer structure change |
| Types.Fraction | L (from Allosteric_Hemoglobin2_MWC) | 7.0529*10^6 | =[T0]/[R0] .. dissociation constant of relaxed <-> tensed change of deoxyhemoglobin tetramer |
| Types.Fraction | c (from Allosteric_Hemoglobin2_MWC) | 0.00431555 | =KR/KT .. ration between oxygen affinities of relaxed vs. tensed subunit |
| Types.Concentration | KR (from Allosteric_Hemoglobin2_MWC) | 0.000671946 | oxygen dissociation on relaxed(R) hemoglobin subunit |
| Types.Concentration | KT (from Allosteric_Hemoglobin2_MWC) | KR/c | oxygen dissociation on tensed(T) hemoglobin subunit |
| Types.AmountOfSubstance | totalAmountOfHemoglobin (from Allosteric_Hemoglobin2_MWC) | 1 |