.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A01A_StomatologicalPreparations.A01AB23_Minocycline.Minocycline

Information

name:Minocycline
ATC code:A01AB23
route:oral
n-compartments2

Minocycline is a semisynthetic tetracycline antibiotic, primarily used for the treatment of a variety of bacterial infections, including acne, respiratory tract infections, urinary tract infections, and certain sexually transmitted diseases. It is approved and widely used today, both topically and systemically.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult subjects after oral administration of 200 mg minocycline. Parameters reflect population mean values.

References

  1. Pardos, SL, et al., & MacGowan, AP (2024). Population pharmacokinetics/pharmacodynamics of minocycline plus rifampicin in patients with complicated skin and skin structure infections caused by MRSA. The Journal of antimicrobial chemotherapy 79(12) 3303–3312. DOI:10.1093/jac/dkae363 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39412246

  2. Hnot, ML, et al., & Papich, MG (2015). Effect of feeding on the pharmacokinetics of oral minocycline in healthy research dogs. Veterinary dermatology 26(6) 399–e93. DOI:10.1111/vde.12246 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26283447

  3. Athanassa, Z, et al., & Tsakris, A (2025). Population pharmacokinetic model of oral minocycline in critically ill adult patients with ventilator-associated pneumonia. The Journal of antimicrobial chemotherapy 80(5) 1420–1426. DOI:10.1093/jac/dkaf090 PUBMED:https://pubmed.ncbi.nlm.nih.gov/40132622

Revisions


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