.Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AB22_AvalglucosidaseAlfa.AvalglucosidaseAlfa .Pharmacolibrary.Drugs.A_AlimentaryTractAndMetabolism.A16A_OtherAlimentaryTractAndMetabolismProducts.A16AB22_AvalglucosidaseAlfa.AvalglucosidaseAlfa| name: | AvalglucosidaseAlfa | |
| ATC code: | A16AB22 | |
| route: | intravenous | |
| compartments: | 2 | |
| dosage: | 2000 | mg |
| volume of distribution: | 56.1 | L |
| clearance: | 17.3 | mL/min |
| other parameters in model implementation | ||
Avalglucosidase alfa is a recombinant human acid alpha-glucosidase enzyme indicated for long-term enzyme replacement therapy in patients with Pompe disease (acid alpha-glucosidase deficiency). It is approved for use in the treatment of late-onset Pompe disease.
Pharmacokinetic parameters reported in adult subjects with late-onset Pompe disease after intravenous administration.