.Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B01A_AntithromboticAgents.B01AE01_Desirudin.Desirudin .Pharmacolibrary.Drugs.B_BloodAndBloodFormingOrgans.B01A_AntithromboticAgents.B01AE01_Desirudin.Desirudin| name: | Desirudin | |
| ATC code: | B01AE01 | route: | subcutaneous |
| compartments: | 1 | |
| dosage: | 15 | mg |
| volume of distribution: | 0.25 | L |
| clearance: | 1.5 | L/h |
| other parameters in model implementation | ||
Desirudin is a recombinant hirudin, a direct thrombin inhibitor used for prophylaxis of deep vein thrombosis (DVT) in patients undergoing elective hip replacement surgery. It acts by inhibiting free and clot-bound thrombin. Desirudin is approved for medical use but is not widely available in all countries.
Pharmacokinetic parameters reported in healthy adults after subcutaneous administration.