name: | Diltiazem |
ATC code: | C05AE03 | route: | oral |
n-compartments | 2 |
Diltiazem is a calcium channel blocker used primarily for the treatment of hypertension, angina pectoris, and certain types of arrhythmias. It is an approved and widely used medication today.
Pharmacokinetic parameters reported in healthy adult volunteers after single oral immediate-release dose.
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Xu, Y, et al., & Shin, JI (2022). Concomitant Use of Diltiazem With Direct Oral Anticoagulants and Bleeding Risk in Atrial Fibrillation. Journal of the American Heart Association 11(14) e025723–None. DOI:10.1161/JAHA.122.025723 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35861836
Guan, XF, et al., & Zuo, XC (2018). Population Pharmacokinetic Modeling of Diltiazem in Chinese Renal Transplant Recipients. European journal of drug metabolism and pharmacokinetics 43(1) 55–62. DOI:10.1007/s13318-017-0425-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/28646274