name: | Citicoline_1 | |
ATC code: | N06BX06_1 | route: | intravenous |
compartments: | 2 | |
dosage: | 1000 | mg |
volume of distribution: | 1.14 | L |
clearance: | 0.26 | L/h/kg |
other parameters in model implementation |
Citicoline (CDP-choline) is an endogenous nucleotide involved in the biosynthesis of phosphatidylcholine, a component of cell membranes. It is used as a neuroprotective agent in the management of stroke, traumatic brain injury, and cognitive impairment. It is available as a supplement/medication in some countries, but its clinical efficacy remains debated and it is not FDA approved in the United States.
Pharmacokinetic parameters in healthy adults following intravenous bolus injection.