.Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AB02_Naphazoline.Naphazoline .Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AB02_Naphazoline.Naphazoline| name: | Naphazoline |
| ATC code: | R01AB02 | route: | topical |
| n-compartments | 1 |
Naphazoline is an imidazoline derivative and a sympathomimetic vasoconstrictor primarily used as a topical decongestant in ophthalmology for eye redness and in nasal preparations for relief of nasal congestion. It acts as an alpha-adrenergic receptor agonist. Naphazoline has been approved and is still used in many over-the-counter ophthalmic and nasal products.
Estimated pharmacokinetic model parameters for topical ocular or nasal administration in adult humans; no pharmacokinetic studies found quantifying naphazoline PK parameters in the published literature.