.Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AC02_Levocabastine.Levocabastine .Pharmacolibrary.Drugs.R_RespiratorySystem.R01A_DecongestantsAndOtherNasalPreparationsForTopical.R01AC02_Levocabastine.Levocabastine| name: | Levocabastine |
| ATC code: | R01AC02 | route: | ocular |
| n-compartments | 1 |
Levocabastine is a selective second-generation antihistamine used primarily for the treatment of allergic conjunctivitis and rhinitis. It acts as a potent and selective H1 receptor antagonist and has been used in eye drops and nasal sprays for symptomatic relief of allergic reactions. Levocabastine is still marketed and approved in some countries, mostly in topical ocular or nasal formulations.
Pharmacokinetic parameters reported in healthy adult volunteers after a single 0.5 mg ocular (eye drop) dose.
Heykants, J, et al., & Woestenborghs, R (1995). The pharmacokinetic properties of topical levocabastine. A review. Clinical pharmacokinetics 29(4) 221–230. DOI:10.2165/00003088-199529040-00002 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8549024