.Pharmacolibrary.Drugs.R_RespiratorySystem.R03B_OtherDrugsForObstructiveAirwayDiseasesInhalants.R03BB01_IpratropiumBromide.IpratropiumBromide

Information

Ipratropium bromide is an anticholinergic medication used as a bronchodilator for the relief of bronchospasm associated with chronic obstructive pulmonary disease (COPD) and asthma. It is administered via inhalation, approved and widely used for respiratory diseases.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following inhalation of ipratropium bromide.

References

1. Panning, CA, & DeBisschop, M (2003). Tiotropium: an inhaled, long-acting anticholinergic drug for chronic obstructive pulmonary disease. Pharmacotherapy 23(2) 183–189. DOI:10.1592/phco.23.2.183.32082 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12587807

2. MacGregor, TR, et al., & Wood, CC (2016). Efficiency of Ipratropium Bromide and Albuterol Deposition in the Lung Delivered via a Soft Mist Inhaler or Chlorofluorocarbon Metered-Dose Inhaler. Clinical and translational science 9(2) 105–113. DOI:10.1111/cts.12387 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26945929

3. Lee, YH, et al., & Noh, GJ (2016). Efficiency of a New Mesh-Type Nebulizer (NE-SM1 NEPLUS) for Intrapulmonary Delivery of Ipratropium Bromide in Surgical Patients. Basic & clinical pharmacology & toxicology 118(4) 313–319. DOI:10.1111/bcpt.12499 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26440415

Revisions

• 06/2025 initial generated model