name: | Nepafenac |
ATC code: | S01BC10 | route: | ophthalmic |
n-compartments | 1 |
Nepafenac is a nonsteroidal anti-inflammatory drug (NSAID) used as an ophthalmic solution to treat pain and inflammation associated with cataract surgery. It is a prodrug rapidly converted to amfenac in ocular tissues and is approved for topical ophthalmic use.
Pharmacokinetic parameters in healthy adult human eyes after single or multiple topical ophthalmic administrations (0.1% nepafenac solution, typical clinical dose). The presented data pertain to the conversion to amfenac (active metabolite) in the aqueous humor.